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Streptococcus suis,an Important Cause of Adult Bacterial Meningitis in Northern Vietnam
Authors:Heiman F. L. Wertheim  Huyen Nguyen Nguyen  Walter Taylor  Trinh Thi Minh Lien  Hoa Thi Ngo  Thai Quoc Nguyen  Bich Ngoc Thi Nguyen  Ha Hong Nguyen  Ha Minh Nguyen  Cap Trung Nguyen  Trinh Tuyet Dao  Trung Vu Nguyen  Annette Fox  Jeremy Farrar  Constance Schultsz  Hien Duc Nguyen  Kinh Van Nguyen  Peter Horby
Abstract:

Background

Streptococcus suis can cause severe systemic infection in adults exposed to infected pigs or after consumption of undercooked pig products. S. suis is often misdiagnosed, due to lack of awareness and improper testing. Here we report the first fifty cases diagnosed with S. suis infection in northern Viet Nam.

Methodology/Principal Findings

In 2007, diagnostics for S. suis were set up at a national hospital in Hanoi. That year there were 43 S. suis positive cerebrospinal fluid samples, of which S. suis could be cultured in 32 cases and 11 cases were only positive by PCR. Seven patients were blood culture positive for S. suis but CSF culture and PCR negative; making a total of 50 patients with laboratory confirmed S. suis infection in 2007. The number of S. suis cases peaked during the warmer months.

Conclusions/Significance

S. suis was commonly diagnosed as a cause of bacterial meningitis in adults in northern Viet Nam. In countries where there is intense and widespread exposure of humans to pigs, S. suis can be an important human pathogen.
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