Risk factors associated with the loss of cartilage volume on weight-bearing areas in knee osteoarthritis patients assessed by quantitative magnetic resonance imaging: a longitudinal study |
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| Authors: | Jean-Pierre Pelletier Jean-Pierre Raynauld Marie-Josée Berthiaume François Abram Denis Choquette Boulos Haraoui John F Beary Gary A Cline Joan M Meyer Johanne Martel-Pelletier |
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| Institution: | (1) Osteoarthritis Research Unit, University of Montreal Hospital Center, H2L 4M1, 1560 Sherbrooke Street East, Montreal, QC, Canada;(2) Radiology Department, Maisonneuve-Rosemont Hospital, H1T 2M4, 5415, boulevard de l'Assomption, Montreal, QC, Canada;(3) Research & Development, ArthroVision, H2K 1B6, 1871 Sherbrooke Street East, Montreal, QC, Canada;(4) Health Care Research Center, Procter & Gamble Pharmaceuticals, 45040-9462, 8700 Mason-Montgomery Road, Mason, OH, USA |
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| Abstract: | The objective of this study was to identify, on a symptomatic knee osteoarthritis (OA) cohort, the risk factors associated
with the progression of the disease. More specifically, we investigated the correlation between knee cartilage volume loss
from subregions over the span of 24 months by means of quantitative magnetic resonance imaging (qMRI) with demographic, clinical,
radiological, and MRI structural changes. |
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