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Calcium content and concretions of pineal glands of young and old rats
Authors:Willy Humbert  Paul Pévet
Institution:(1) Laboratoire de Zoologie, CNRS-URA 1332 ldquoNeurobiologie des fonctions rythmiques et saisonnièresrdquo, 12, Rue de l'Université, F-67000 Strasbourg, France
Abstract:Summary Calcium content and pineal concretions were studied in young (2–3 months) and old (28 months) Wistar rats. Samples, deep-frozen by liquid propane/isopentane and freeze-dried were analysed by means of X-ray microanalysis in a scanning electron microscope. Total semi-quantitative measurements revealed that pineals of old rats showed a marked increase of calcium compared with the pineals of young rats. It is thus suggested that a calcium-rich environment is responsible for the growth of pineal concretions, which only appear in old rats. Pineal calcifications in rats could thus be an indicator of aging and/or of a degenerating state.
Keywords:Pineal gland  Concretions  Calcium  X-ray microanalysis  Rat (Wistar)
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