Synthesis of 5,8,11,14,17-eicosapentaenic acid |
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Authors: | Iu Iu Belosludtsev P M Demin G I Miagkova D A Zabolotski? R P Evstigneeva |
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Abstract: | A synthetic route to 5,8,11,14,17-eicosapentaynoic acid, an acetylenic precursor of 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid, has been developed based on condensation of a propargyl synthon with omega-acetylenic fragments. Physico-chemical constants and spectral characteristics (IR, 1H-NMR, and mass-spectrometry) of the target and intermediate compounds are given. |
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