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A comparison of the take of embryonic amygdala and visual cortex transplants in the rat brain in connection with the possible compensation of functional disorders]
Authors:E A Lushchekina  V S Lushchekin  N M Khonicheva
Abstract:Transplantation of embryonic (E17-18) visual cortex and amygdala was performed into corresponding damaged areas of the adult rat brain. It was shown in Nissl and Golgi preparations (by comparing qualitative and quantitative findings) that 2-6 months after operation the grafts were successful in case of putting them into the corresponding brain areas (cortex to cortex, or amygdala to amygdala). Graft's integration resulted in a selective increase of dendrite length and ramification towards the area of graft-host interface both in amygdala and visual cortex grafts. In case of inadequate graft-host integration the stratification of the grafted visual cortex could be observed. The structural reorganization of grafted neurones is compared with physiological and behavioural findings during the recovery processes in damaged brain.
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