|
|||||
|
|
Structure of the fluorescent nucleoside of yeast phenylalanine transfer ribonucleic acid |
|
| Authors: | Steven H Blobstein Ronald Gebert Dezider Grunberger Koji Nakanishi IBernard Weinstein |
| Institution: | Institute of Cancer Research and Departments of Medicine and Biochemistry, College of Physicians and Surgeons, Columbia University, New York, New York 10032 USA |
| Abstract: | The structure of enzymatically isolated Y nucleoside of yeast phenylalanine tRNA was established by comparing its absorption, fluorescence, and mass spectra to that of the free base. The site of ribosylation was tentatively deduced by comparing the behavior under acid conditions of the natural nucleoside to that of synthetic Y nucleoside analogs. Our results indicate that the aglycone of the enzymatically isolated nucleoside has the same structure as the free base excised by acid treatment of phenylalanine tRNA, and that the ribose is probably attached to the N-3 position of the tricyclic nucleus. |
| Keywords: | National Institutes of Health Predoctoral Fellow (GM 50055) To whom to address correspondence Mailing address: Institute of Cancer Research 99 Fort Washington Avenue New York NY 10032 |
| 本文献已被 ScienceDirect 等数据库收录！ | |