Fluid lipid fraction in rod outer segment membrane |
| |
Authors: | M Pontus M Delmelle |
| |
Institution: | Département de Physique Atomique et Moléculaire, Université de Liègre, 4000 Sart Tilman par Liège 1 Belgium |
| |
Abstract: | Rod outer segment membrane is analyzed using the spin label technique by means of two probes. The solubility of the first label, 2,2,6,6-tetramethylpiperidin-1-oxyl, is correlated with the membrane fluidity which is measured using a stearic acid spin probe. The two values are compared to the solubility-fluidity relationship which characterizes a model system in which all lipids are in a fluid state. The analysis leads to the conclusion that only two thirds of the membrane lipids are fluid. This conclusion is reinforced by the observation that partial lipid removal leaves rigid lipids associated with the rhodopsin molecules. |
| |
Keywords: | TEMPO 2 2 6 6-tetramethylpiperidin-1-oxyl |
本文献已被 ScienceDirect 等数据库收录! |
|