Nuclear and cytoplasmic glutamate dehydrogenases (NADP-dependent) in <span class="math"><math><mtext>Saccharomyces cerevisiae</mtext></math></span>期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Nuclear and cytoplasmic glutamate dehydrogenases (NADP-dependent) in $Saccharomyces cerevisiae$

Authors:	Laura Camardella Guido di Prisco Felice Garofano Anna Maria Guerrini

Institution:	International Institute of Genetics and Biophysics, CNR, Via Marconi 10, 80125 Naples, Italy

Abstract:	The intracellular localization of NADP-dependent glutamate dehydrogenase has been studied in $Saccharomyces cerevisiae$ .Beside cytoplasmic GDH, enzyme activity has been found to be associated with the nuclear fraction in amounts comparable to those reported in nuclei of higher organisms.The yield and distribution of both GDH activities have been analyzed in mutants showing, under particular growth conditions, defective mitochondrial functions.

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