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Differential adhesive properties of the surface of human blood flukesSchistosoma mansoni
Authors:Ronald B Podesta  John F Boyce  Samuel Schurch  Shona S McDiarmid
Institution:(1) Department of Zoology, University of Western Ontario, N6A 5B7 London, Ontario, Canada;(2) Department of Biophysics, University of Western Ontario, N6A 5B7 London, Ontario, Canada;(3) Department of Medicine, University of Western Ontario, N6A 5B7 London, Ontario, Canada
Abstract:While infecting a vertebrate host, blood flukes (Schistosoma mansoni) must continually resist adhesions by immune effector cells. However, the male and female schistosomes must adhere to one another in order to establish and maintain the sexual pairing process after 4 wk postinfection. Using a contact angle method, the relative adhesiveness of male and female parasites were determined. Results indicate that schistosomes restrict effector cell adhesion through developmental, sexual, and regional differences in adhesive properties.
Keywords:Schistosoma mansoni            interfacial free energy  surface adhesion  surface coat  Gram-negative bacteria  polyethyleneglycol  dextran  cell adhesion
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