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Genetic Determinants of Height Growth Assessed Longitudinally from Infancy to Adulthood in the Northern Finland Birth Cohort 1966 |
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| Authors: | Ulla Sovio Amanda J. Bennett Iona Y. Millwood John Molitor Paul F. O'Reilly Nicholas J. Timpson Marika Kaakinen Jaana Laitinen Jari Haukka Demetris Pillas Ioanna Tzoulaki Jassy Molitor Clive Hoggart Lachlan J. M. Coin John Whittaker Anneli Pouta Anna-Liisa Hartikainen Nelson B. Freimer Elisabeth Widen Leena Peltonen Paul Elliott Mark I. McCarthy Marjo-Riitta Jarvelin | |
| Abstract: | Recent genome-wide association (GWA) studies have identified dozens of common variants associated with adult height. However, it is unknown how these variants influence height growth during childhood. We derived peak height velocity in infancy (PHV1) and puberty (PHV2) and timing of pubertal height growth spurt from parametric growth curves fitted to longitudinal height growth data to test their association with known height variants. The study consisted of N | |
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