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昆虫杆状病毒的蜕皮甾体尿苷二磷酸葡糖转移酶
引用本文:闫庆生,欧阳晓光,李充璧,庞义. 昆虫杆状病毒的蜕皮甾体尿苷二磷酸葡糖转移酶[J]. 生物化学与生物物理进展, 1999, 26(3): 241-242
作者姓名:闫庆生  欧阳晓光  李充璧  庞义
作者单位:中山大学昆虫学研究所,生物防治国家重点实验室,广州,510275
基金项目:国家自然科学基金重点项目(39730030)及“九五”国家重点科技攻关项目(96-01-01-04)资助.
摘    要:昆虫杆状病毒的蜕皮甾体尿苷二磷酸葡糖转移酶(ecdysteroid UDP-glucosyltransferase, EGT)能催化UDP-糖基连接到蜕皮甾体上,使之失活,从而阻止或推迟蜕皮,有利于病毒复制,所以缺失egt基因的病毒能改良杀虫效果,如加速死亡和减少摄食量等.最近几年的研究进展主要集中在基因和蛋白质的一级结构、酶催化反应、以及对宿主的生物学功能等几方面.

关 键 词:昆虫杆状病毒,蜕皮甾体尿苷二磷酸葡糖转移酶,egt基因
收稿时间:1998-03-10
修稿时间:: 1998-03-

Insect Baculovirus-encoded Ecdysteroid UDP-Glucosyltransferases
YAN Qing-Sheng,OUYANG Xiao-Guang,LI Chong-Bi and PANG Yi. Insect Baculovirus-encoded Ecdysteroid UDP-Glucosyltransferases[J]. Progress In Biochemistry and Biophysics, 1999, 26(3): 241-242
Authors:YAN Qing-Sheng  OUYANG Xiao-Guang  LI Chong-Bi  PANG Yi
Affiliation:Institute of Entomology and State Key Laboratory for Biocontrol, Zhongshan University, Guangzhou 510275, China;Institute of Entomology and State Key Laboratory for Biocontrol, Zhongshan University, Guangzhou 510275, China;Institute of Entomology and State Key Laboratory for Biocontrol, Zhongshan University, Guangzhou 510275, China;Institute of Entomology and State Key Laboratory for Biocontrol, Zhongshan University, Guangzhou 510275, China
Abstract:Insect baculovirus-encoded ecdysteroid UDP-glucosyltransferase (EGT) are not essential enzymes which catalyze the conjugation of ecdysteroids with UDP-glucose. In vivo, the sugar conjugation of ecdysteroids by EGT causes suppression of host molting. The deletion of egt gene actually improves the pesticidal properties of the baculovirus. Insects infected by an egt-minus virus display reduce feeding and earlier death than those infected by wild-type virus. The recent advances in the studies of the egt gene and protein, EGT-catalyzed conjugation, EGT effects on host development and suvival as well as biological role of EGT are introduced.
Keywords:insect baculovirus   ecdysteroid UDP glucosyltransferase   egt gene  
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