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Discovery of the first antibacterial small molecule inhibitors of MurB |
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| Authors: | Bronson Joanne J DenBleyker Kenneth L Falk Paul J Mate Robert A Ho Hsu-Tso Pucci Michael J Snyder Lawrence B |
| Affiliation: | Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, CT 06492, USA. |
| Abstract: | A series of imidazolinone analogues was synthesized and shown to possess potent MurB inhibitory as well as good antibacterial activity. |
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