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Animal variation in alanine uptake by rabbit ileal mucosa
Authors:J.Y.F. Paterson  M.W. Smith  F.V. Sepúlveda
Affiliation:A.R.C. Institute of Animal Physiology, Babraham, Cambridge CB2 4AT U.K.
Abstract:Alanine uptake by rabbit ileal mucosa has been measured in the presence and absence of Na+ to establish the characteristics of biological variation. Common Km values, calculated for two systems of alanine entry, were used for estimation of two Jmax values for individual rabbits. The distribution of Jmax1 and Jmax2 within the population was normal and there was minimal interaction between these two parameters, judged by a cross-correlation analysis. Ways of processing data to account for this type of animal variation are discussed.
Keywords:Alanine transport  Biological variation  (Intestinal mucosa)
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