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The proteasome inhibitor lactacystin enhances GSH synthesis capacity by increased expression of antioxidant components in an Nrf2-independent,but p38 MAPK-dependent manner in rat colorectal carcinoma cells |
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| Authors: | Nils-Erik Huseby Chandra Ravuri Ugo Moens |
| Institution: | 1. Tumor Biology Research Group, Department of Medical Biology, Faculty of Health Sciences, University of Troms?, Troms?, Norwaynils-erik.huseby@uit.no;3. Tumor Biology Research Group, Department of Medical Biology, Faculty of Health Sciences, University of Troms?, Troms?, Norway;4. Molecular Inflammation Research Group, Department of Medical Biology, Faculty of Health Sciences, University of Troms?, Troms?, Norway |
| Abstract: | |
| Keywords: | Cystine/glutamate transporter γ-glutamyltransferase glutamate cysteine ligase glutathione regulation oxidative stress proteasomal inhibitors |