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Phenolics from Tanacetum sinaicum (Fresen.) Delile ex Bremer & Humphries (Asteraceae)
Institution:1. Chemistry Department, Science College, Qassim University, Buraidah, Saudi Arabia;2. Chemistry Branch, Department of Science and Mathematics, Faculty of Petroleum and Mining Engineering, Suez University, 43721 Suez, Egypt;3. Marine Chemistry lab, National Institute of Oceanography & Fisheries, Suez, Egypt;4. Chemistry Department, Science College, Suez University, 43518 Suez, Egypt;5. Chemistry of Medicinal Plants Department, National Research Centre, 12622, 33 El Bohouth St., Dokki, Giza, Egypt
Abstract:The phytochemical investigation on Tanacetum sinaicum (Fresen.) Delile ex Bremer & Humphries led to the isolation of eight flavonoid aglycones (apigenin 1, acacetin 2, luteolin 3, chrysoeriol 4, cirsilineol 5, jaceidin 6, chrysosplenetin 7 and vitexicarpin; casticin 8), four flavonoid glycosides (apigenin 7-O-β-glucopyranoside 9, apigenin 7-O-β-glucuronide 10, luteolin 7-O-β-glucopyranoside 11 and luteolin 7-O-β-glucuronide 12) and three phenolics (4-hydroxy-3-methoxy benzoic acid 13, 3,4-dimethoxy benzoic acid 14 and 4-hydroxy acetophenone 15). Their structures were determined by chemical and spectroscopic analysis. Among them, compounds 1–3, 9, 11, 13 and 14 were reported for the first time from T. sinaicum. The chemotaxonomic significance of the isolated flavonoids was also summarized.
Keywords:Asteraceae  Anthemideae  Flavonoids  Chemotaxonomy
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