11α‐Ethoxy‐β‐boswellic Acid and Nizwanone,a New Boswellic Acid Derivative and a New Triterpene,Respectively, from Boswellia sacra |
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| Authors: | Ahmed Al‐Harrasi Liaqat Ali Najeeb Ur?Rehman Javid Hussain Hidayat Hussain Ahmed Al‐Rawahi Tania Shamim?Rizvi |
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| Institution: | 1. Department of Biological Sciences and Chemistry, University of Nizwa, P.O. Box 33, Postal Code 616, Birkat Al Mauz, Nizwa, Sultanate of Oman (phone: +968‐92828487;2. fax: +968‐25446289);3. International Center for Chemical and Biological Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi‐75270, Pakistan |
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| Abstract: | A new boswellic acid derivative, 11α‐ethoxy‐β‐boswellic acid (EBA; 1 ) and a new ursane‐type triterpene, named nizwanone ( 2 ), were isolated from Omani frankincense Boswellia sacra Flueck . together with two known compounds papyriogenin B and rigidenol. The structures of 1 and 2 were elucidated by detailed spectroscopic analysis using 1H‐ and 13C‐NMR, 1H,1H‐COSY, HMQC, HMBC, and HR‐EI‐MS techniques. The relative configurations of 1 and 2 were assigned by comparative analysis of the NMR spectral data with those of known analogs together with NOESY experiments. Structures of known compounds were identified by comparison with the reported data. |
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| Keywords: | Boswellia sacra β ‐Boswellic acid 11α ‐ethoxy‐ Ursanes Nizwanone Triterpenes |
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