Synthesis of a mannosyl phosphoryl polyprenol by the cellular slime mold Dictyostelium discoideum |
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| Authors: | Edmund V. Crean Edward F. Rossomando |
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| Affiliation: | Department of Oral Biology, University of Connecticut Health Center, Farmington, Conn. 06032, U.S.A. |
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| Abstract: | A membrane fraction isolated from the cellular slime mold Dictyostelium discoideum was incubated with GDP-[14C]mannose and found to catalyze the incorporation of [14C]mannose into an endogenous acceptor to yield a product with the chemical and chromatographic properties of a polyprenol phosphate sugar derivative. These result suggest that D. discoideum can synthesize a mannosyl phosphoryl polyprenol. |
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