Abietane Diterpenes from Hyptis suaveolens |
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| Authors: | Saowanee Prawatsri Apichart Suksamrarn Anon Chindaduang Thitima Rukachaisirikul |
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| Affiliation: | 1. Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand, (phone: +662‐2‐3195112;2. fax: +662‐2‐3108381) |
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| Abstract: | Investigation of the constituents of the whole plant of Hyptis suaveolens led to the isolation of three new abietane diterpenes, isosuaveolic acid ( 1 ), 8α,9α‐epoxysuaveolic acid ( 2 ), and 14‐O‐methylsuaveolic acid ( 3 ), together with eleven known compounds. The structures of 1 – 3 were established by spectroscopic methods and chemical correlations. Some isolates were tested for their antimycobacterial and cytotoxic activities. |
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| Keywords: | Hyptis suaveolens Abietanes Diterpenes Antimycobacterial activity Cytotoxic activity |
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