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An Insight to Chiral Monolith for Enantioselective Nano and Micro HPLC: Preparation and Applications
Authors:Robert Healey  Ashraf Ghanem
Institution:Chirality Program, Faculty of Applied Science, University of Canberra, , Australian Capital Territory (ACT), 2617 Australia
Abstract:This review gives an overview of chiral separation principles and their application in enantioselective nano/micro high performance liquid chromatography (n/μ‐HPLC) using chiral monolith. In particular, developments in silica and polymer chiral monolithic stationary phases are presented. The preparation and applications of chiral monoliths, the basic chiral separation principles and the mechanisms are discussed. Chirality 25:314–323, 2013. © 2013 Wiley Periodicals, Inc.
Keywords:nano‐HPLC  monolith  chiral selectors  chiral separation  silica monolith  HPLC
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