Synthesis,Physicochemical Properties,and in vitro Antibacterial Screening of Palladium(II) Complexes Derived from Thiosemicarbazone |
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| Authors: | Mohammad Azam Ismail Warad Saud I. Al‐Resayes M. Rafiq Siddiqui M. Oves |
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| Affiliation: | 1. Department of Chemistry, King Saud University, P.O. Box 2455, Riyadh 11451, KSA, (phone: +966‐596441517);2. Department of Agricultural Microbiology, Faculty of Agricultural Sciences, Aligarh Muslim University, Aligarh 202002, India |
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| Abstract: | A new series of PdII complexes derived from thiosemicarbazone has been synthesized. The synthesized PdII complexes have been characterized on the basis of elemental analyses, FT‐IR, 1H‐ and 13C‐NMR, UV/VIS, and thermal studies. A square‐planar geometry has been assigned around PdII ions on the basis of results obtained from UV/VIS studies. The thiosemicarbazone ligand and its PdII complexes have been screened against Gram‐positive (Bacillus subtilis and Staphylococcus aureus) and Gram‐negative (Escherichia coli and Pseudomonas aeruginosa) bacteria in vitro as growth‐inhibiting agents, and the results revealed significant antibacterial activities. |
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| Keywords: | Palladium complexes Thiosemicarbazones Antibacterial activity |
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