Actinotetraoses I–K: Tetrasaccharide Metabolites Produced by an Insect‐Derived Actinobacteria,Amycolatopsis sp. HCa1 |
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| Authors: | Zhi‐Kai Guo Rui‐Hua Jiao Hao‐Fu Dai Wen‐Li Mei Ren‐Xiang Tan Hui‐Ming Ge |
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| Institution: | 1. Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, P.?R. China;2. Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P.?R. China (phone/fax: +86‐25‐83593201) |
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| Abstract: | An isolate of rare actinobacteria strain Amycolatopsis sp. HCa1 obtained from the gut of grasshopper produced seven different metabolites in vitro. The metabolites isolated from its mycelia cakes were characterized by NMR and MS analyses. Actinotetraose hexatiglate (or tigloside; 1 ) with nonreducing glucotetraose skeleton was isolated as a major constituent; three new tetrasaccharide derivatives actinotetraoses I–K ( 2 – 4 , resp.) and three known actinotetraoses A–C ( 5 – 7 , resp.) were also isolated. |
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| Keywords: | Actinomycetes Amycolatopsis species Actinotetraoses I – K Glucosides |
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