Comparative evaluation of Trichosporon asahii susceptibility using ASTY colorimetric microdilution and CLSI M27‐A2 broth microdilution reference methods |
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| Authors: | Ayse Kalkanci Nanthawan Mekha Natteewan Poonwan Koichi Makimura Takashi Sugita |
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| Affiliation: | 1. Gazi University Faculty of Medicine, Department of Microbiology, Besevler, Ankara, 06500 Turkey;2. Department of Microbiology, Meiji Pharmaceutical University, Kiyose, Tokyo 2004‐8588 Japan;3. Mycology Laboratory, National Institute of Health, Department of Medical Sciences, Nonthaburi, 11000 Thailand;4. Department of Molecular Biology and Gene Diagnosis, Institute of Medical Mycology and Genome Research Center, Graduate School of Medical Science and Faculty of Medicine, Teikyo University, Hachioji, Tokyo 192‐0395 |
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| Abstract: | The in vitro activity of AMPH‐B, 5‐FC, FLCZ, MCZ, ITCZ, and VRCZ against 50 isolates of T. asahii was determined using CLSI M27‐A2 microdilution and ASTY colorimetric methods. Observed agreement ranged from 96 to 100% according to the drug. Overall, the agreement between two methods was 97.7%. The ASTY colorimetric method was thus determined to be comparable to the CLSI reference method when testing the susceptibility of T. asahii to a variety of antifungal agents. |
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| Keywords: | ASTY CLSI susceptibility Trichosporon asahii |
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