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Recurrent design patterns in the feedback regulation of the mammalian signalling network |
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| Authors: | Stefan Legewie Hanspeter Herzel Hans V Westerhoff Nils Blüthgen |
| Affiliation: | 1. Institute for Theoretical Biology, Humboldt University, Berlin, Germany;2. Manchester Centre for Integrative Systems Biology, The University of Manchester, Manchester, UK;3. Manchester Interdisciplinary Biocentre, School of Chemical Engineering and Analytical Sciences, The University of Manchester, Manchester, UK;4. Department of Molecular Cell Physiology, Faculty of Earth and Life Sciences, Netherlands Institute for Systems Biology, Vrije Universiteit, Amsterdam, The Netherlands |
| Abstract: | |
| Keywords: | evolutionary trade‐off gene regulation protein turnover signal transduction |