Magnetic resonance spectroscopy in vivo |
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| Institution: | 1. Neonatal Services, Royal Women''s Hospital, Locked Bag 300, Parkville 3052, Australia;2. Victorian Infant Brain Studies, Murdoch Childrens Research Institute, 4th Floor, Flemington Road, Parkville, VIC 3052, Australia;3. Department of Physiotherapy, School of Health Sciences, University of Melbourne, Carlton, Australia;1. Department of Developmental and Social Psychology, Sapienza University of Rome, Via dei Marsi, 78, 00185 Rome, Italy;2. Department of Dynamic and Clinical Psychology, Sapienza University of Rome, Via degli Apuli 1, 00185 Rome, Italy;3. Department of Neuroscience and Neuro-rehabilitation, Unit of Clinical Psychology, Bambino Gesù Children''s Hospital, IRCCS, Piazza S. Onofrio 4, 00165 Rome, Italy;4. Department of Medical and Surgical Neonatology, Bambino Gesù Children''s Hospital, IRCCS, Piazza S. Onofrio 4, 00165 Rome, Italy;5. Hospital Policlinico Umberto I, Viale Regina Elena 324, 00161 Rome, Italy;1. Department of Health Sciences, University of Leicester, Leicester, UK;2. Department of Psychology and Health Sciences Research Institute and Division of Mental Health and Wellbeing, Warwick Medical School, University of Warwick, Coventry, UK;1. Laboratory of Metabolic Disorders, School of Applied Sciences, University of Campinas, UNICAMP, Limeira, São Paulo, Brazil;2. Obesity and Comorbidities Research Center, University of Campinas, Campinas, Brazil |
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| Abstract: | Nuclear magnetic resonance (NMR) has become an important non-invasive investigative technique in medicine and biology. The most recent development has been the ability to perform magnetic resonance spectroscopy (MRS) in selected regions within the human body. Such volumes can be selected by techniques which fall into the following broad catagories: surface coil methods, surface coils with depth selection, volume selection and chemical shift mapping. The latter two methods use magnetic field gradients, present on magnetic resonance imaging systems, to select the volume. MRS can be used to measure phosphorus and proton metabolites and hence study tissue biochemistry in-vivo. |
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