Identification of the cell surface receptor for FC3-2, FC3-3 and FC3-6 bacteriophages from Klebsiella pneumoniae |
| |
| Authors: | Juan M Tomás Vicente J Benedi Juan T Jofre |
| |
| Institution: | Department of Microbiology, Faculty of Biology, University of Barcelona, Barcelona, Spain |
| |
| Abstract: | FC3-2, FC3-3 and FC3-6 are different Klebsiella-specific bacteriophages isolated on Klebsiella pneumoniae strain C3. The common bacteriophage receptor for these phages was shown to be the lipopolysaccharide (LPS), specifically the high-molecular-weight polysaccharide fraction (O-antigen). Mutants resistant to these phages were isolated and found to be devoid of lipopolysaccharide O-antigen by several criteria. We concluded that no other outer membrane (OM) molecules were involved in phage binding. At least 2 different types of lipopolysaccharide-core mutant were obtained. |
| |
| Keywords: | Klebsiella pneumoniae Lipopolysaccharide Bacteriophage receptor |
| 本文献已被 ScienceDirect 等数据库收录！ |
