Transgenerational inheritance of longevity: epigenetic mysteries abound |
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| Authors: | Berger Shelley L |
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| Affiliation: | Department of Cell and Developmental Biology, 1057 BRB, 421 Curie Boulevard, University of Pennsylvania, Philadelphia, PA 19104, USA. bergers@upenn.edu |
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| Abstract: | Transgenerational inheritance of epigenetic characteristics in plants has been reported, whereas nongenetic persistence of complex phenotypes in animals is controversial. A recent report by Anne Brunet and colleagues describes a fascinating example of persistence across generations of extended life span in worm and explores whether epigenetic mechanisms account for the longevity. |
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