Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Abstract:
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Highlights? Lysosome-related organelles in intestinal cells are the major site of zinc storage ? The cation diffusion facilitator protein CDF-2 transports zinc into gut granules ? Gut granules adopt a bilobed morphology in high dietary zinc ? Zinc storage in gut granules promotes zinc detoxification and mobilization
