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A basophil-neuronal axis promotes itch
Authors:Fang Wang  Anna M. Trier  Fengxian Li  Seonyoung Kim  Zhen Chen  Jiani N. Chai  Madison R. Mack  Stephanie A. Morrison  Jennifer D. Hamilton  Jinok Baek  Ting-Lin B. Yang  Aaron M. Ver Heul  Amy Z. Xu  Zili Xie  Xintong Dong  Masato Kubo  Hongzhen Hu  Chyi-Song Hsieh  Brian S. Kim
Affiliation:1. Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA;2. Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA;3. Department of Dermatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, China;4. Department of Anesthesiology, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong 510282, China;5. Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA;6. Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA;7. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA;8. Department of Dermatology, College of Medicine, Gachon University, Incheon 21565, Korea;9. Division of Allergy and Immunology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA;10. The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;11. Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA;12. Laboratory for Cytokine Regulation, Center for Integrative Medical Science, RIKEN Yokohama Institute, Yokohama 230-0045, Kanagawa Prefecture, Japan;13. Division of Molecular Pathology, Research Institute for Biomedical Science, Tokyo University of Science, Noda 278-0022, Chiba Prefecture, Japan;14. Division of Rheumatology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA;15. Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA;16. Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA
Abstract:
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  • Keywords:allergy  atopic dermatitis  itch  pruritus  IgE  basophils  mast cells  leukotriene  sensory neurons
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