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In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions |
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| Authors: | Hongling Huang Peipei Zhou Jun Wei Lingyun Long Hao Shi Yogesh Dhungana Nicole M Chapman Guotong Fu Jordy Saravia Jana L Raynor Shaofeng Liu Gustavo Palacios Yong-Dong Wang Chenxi Qian Jiyang Yu Hongbo Chi |
| Institution: | 1. Department of Immunology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA;2. Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA;3. Department of Computational Biology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA |
| Abstract: |  |
| Keywords: | T cell memory metabolic heterogeneity terminal effector cell immunometabolism Notch GDP-fucose nutrient signaling cell cycle exit systems immunology |
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