首页 | 本学科首页   官方微博 | 高级检索  
   检索      


In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs
Authors:Lei Sun  Pan Li  Xiaohui Ju  Jian Rao  Wenze Huang  Lili Ren  Shaojun Zhang  Tuanlin Xiong  Kui Xu  Xiaolin Zhou  Mingli Gong  Eric Miska  Qiang Ding  Jianwei Wang  Qiangfeng Cliff Zhang
Institution:1. MOE Key Laboratory of Bioinformatics, Beijing Advanced Innovation Center for Structural Biology & Frontier Research Center for Biological Structure, Center for Synthetic and Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China;2. Tsinghua-Peking Center for Life Sciences, Beijing 100084, China;3. Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing 100084, China;4. NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China;5. Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China;6. Wellcome Trust/Cancer Research UK Gurdon Institute, Department of Genetics, University of Cambridge, Cambridge CB2 1QN, UK;7. Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, CB10 1SA, UK
Abstract:
><ol class=
  • Download : Download high-res image (187KB)
  • Download : Download full-size image
  • Keywords:SARS-CoV-2  RNA secondary structure  host factor  RBP binding prediction  drug reproposing
    本文献已被 ScienceDirect 等数据库收录!
    设为首页 | 免责声明 | 关于勤云 | 加入收藏

    Copyright©北京勤云科技发展有限公司  京ICP备09084417号