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Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity
Authors:Wilfredo F. Garcia-Beltran  Evan C. Lam  Kerri St. Denis  Adam D. Nitido  Zeidy H. Garcia  Blake M. Hauser  Jared Feldman  Maia N. Pavlovic  David J. Gregory  Mark C. Poznansky  Alex Sigal  Aaron G. Schmidt  A. John Iafrate  Vivek Naranbhai  Alejandro B. Balazs
Affiliation:1. Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA;2. Department of Pathology, Brigham and Women’s Hospital, Boston, MA 02115, USA;3. Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA;4. Vaccine and Immunotherapy Center, Massachusetts General Hospital, Boston, MA 02129, USA;5. Pedriatric Infectious Disease, Massachusetts General Hospital for Children, Boston, MA 02114, USA;6. Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA;7. Africa Health Research Institute, Durban 4001, South Africa;8. School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4041, South Africa;9. Max Planck Institute for Infection Biology, Berlin 10117, Germany;10. Dana-Farber Cancer Institute, Boston, MA 02215, USA;11. Center for the AIDS Programme of Research in South Africa, Durban 4001, South Africa
Abstract:
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  • Keywords:COVID-19  SARS-CoV-2  spike  variants  RBD  neutralizing antibodies  escape  mRNA vaccines
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