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SARS-CoV-2 variants B.1.351 and P.1 escape from neutralizing antibodies
Authors:Markus Hoffmann  Prerna Arora  Rüdiger Groß  Alina Seidel  Bojan F Hörnich  Alexander S Hahn  Nadine Krüger  Luise Graichen  Heike Hofmann-Winkler  Amy Kempf  Martin S Winkler  Sebastian Schulz  Hans-Martin Jäck  Bernd Jahrsdörfer  Hubert Schrezenmeier  Martin Müller  Alexander Kleger  Jan Münch  Stefan Pöhlmann
Institution:1. Infection Biology Unit, German Primate Center, Kellnerweg 4, 37077 Göttingen, Germany;2. Faculty of Biology and Psychology, Georg-August-University Göttingen, Wilhelmsplatz 1, 37073 Göttingen, Germany;3. Institute of Molecular Virology, Ulm University Medical Center, Meyerhofstr. 1, 89081 Ulm, Germany;4. Junior Research Group Herpesviruses – Infection Biology Unit, German Primate Center, Kellnerweg 4, 37077 Göttingen, Germany;5. Department of Anaesthesiology, University of Göttingen Medical Center, Göttingen, Georg-August University of Göttingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany;6. Division of Molecular Immunology, Department of Internal Medicine 3, Friedrich-Alexander University of Erlangen-Nürnberg, Glückstraße 6, 91054 Erlangen, Germany;7. Department of Transfusion Medicine, Ulm University, Helmholtzstraße 10, 89081 Ulm, Germany;8. Institute for Clinical Transfusion Medicine and Immunogenetics, German Red Cross Blood Transfusion Service Baden-Württemberg – Hessen and University Hospital Ulm, Helmholtzstraße 10, 89081 Ulm, Germany;9. Department of Internal Medicine 1, Ulm University Hospital, Albert-Einstein-Allee 23, 89081 Ulm, Germany;10. Core Facility Functional Peptidomics, Ulm University Medical Center, Meyerhofstr. 4, 89081 Ulm, Germany
Abstract:
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  • Keywords:SARS-CoV-2  COVID-19  variants  variants of concern  VOC  B  1  1  7  B  1  351  P  1  spike protein  host cell entry  antibodies  neutralization  escape
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