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Aglycone flavonoid brachydin A shows selective cytotoxicity and antitumoral activity in human metastatic prostate (DU145) cancer cells |
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| Authors: | de Oliveira Larissa Cristina Bastos Nunes Higor Lopes Ribeiro Diego Luis do Nascimento Jessyane Rodrigues da Rocha Cláudia Quintino de Syllos Cólus Ilce Mara Serpeloni Juliana Mara |
| Institution: | 1.Department of General Biology, Center of Biological Sciences, State University of Londrina (UEL), Londrina, 86057-970, Brazil ;2.Department of Genetics, Ribeir?o Preto Medical School, University of S?o Paulo (USP), Ribeir?o Preto, S?o Paulo, 14040-903, Brazil ;3.Chemistry Institute, S?o Paulo State University (UNESP), Araraquara, S?o Paulo, 14800-900, Brazil ;4.Department of Chemistry, Center for Exact Sciences and Technology, Federal University of Maranh?o, S?o Luís, 65080-805, Brazil ;5.Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina – UEL, Rodovia Celso Garcia Cid - PR 445 Km 380 Cx. Postal 10.011 - Campus Universitário, Londrina, PR, CEP: 86057-970, Brazil ; |
| Abstract: | Cytotechnology - In prostate cancer, flavonoids possess a wide variety of anticancer effects, focused on the antioxidant/pro-oxidant activity, inactivation of the androgen receptor, cell cycle... |
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