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Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques
Authors:Xuan He  Abishek Chandrashekar  Roland Zahn  Frank Wegmann  Jingyou Yu  Noe B. Mercado  Katherine McMahan  Amanda J. Martinot  Cesar Piedra-Mora  Sidney Beecy  Sarah Ducat  Ronnie Chamanza  Sietske Rosendahl Huber  Marjolein van Heerden  Leslie van der Fits  Erica N. Borducchi  Michelle Lifton  Jinyan Liu  Dan H. Barouch
Affiliation:1. Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA;2. Tufts University Cummings School of Veterinary Medicine, North Grafton, MA 01536, USA;3. Janssen Vaccines & Prevention BV, Leiden, the Netherlands;4. Bioqual, Rockville, MD 20852, USA;5. Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA;6. Massachusetts Consortium on Pathogen Readiness, Boston, MA 02215, USA
Abstract:
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  • Keywords:COVID-19  SARS-CoV-2  vaccination  Ad26.COV2.S  non-human primates  immunology  protection  humoral immunity  memory B cells
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