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SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD,RBD, and S2
Authors:Fatima Amanat  Mahima Thapa  Tinting Lei  Shaza M. Sayed Ahmed  Daniel C. Adelsberg  Juan Manuel Carreño  Shirin Strohmeier  Aaron J. Schmitz  Sarah Zafar  Julian Q. Zhou  Willemijn Rijnink  Hala Alshammary  Nicholas Borcherding  Ana Gonzalez Reiche  Komal Srivastava  Emilia Mia Sordillo  Harm van Bakel
Affiliation:1. Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA;2. Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA;3. Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA;4. AbCellera Biologics Inc., Vancouver, BC V5Y 0A1, Canada;5. Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA;6. Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA;7. Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA;8. Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA;9. The Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA;10. Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA;11. Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, Saint Louis, MO 63110, USA
Abstract:
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  • Keywords:SARS-CoV-2  mRNA vaccination  mAbs  NTD  RBD  spike  plasmablasts
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