Molecular modelling studies on the interactions of human DNA topoisomerase IB with pyridoxal-compounds |
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| Authors: | Christmann-Franck Serge Fermandjian Serge Mirambeau Gilles Der Garabedian P Arsène |
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| Institution: | Département de Biologie et Pharmacologie Structurales, CNRS UMR 8113, Institut Gustave Roussy et ENS Cachan, 61 Avenue du Président Wilson, 94235 Cachan Cedex, France. |
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| Abstract: | Candida guilliermondii and human DNA topoisomerases I are inhibited by PL (pyridoxal), PLP (pyridoxal 5'-phosphate) and PLP-AMP (pyridoxal 5'-diphospho-5'-adenosine) (PL
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