Late activation of interferon-induced genes IFI-54k and IFI-56k in human RH cells infected with tick-borne encephalitis virus |
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| Authors: | Gavrilov B G Monastyrskaia G S Velikodvorskaia T V Filiukova O B Konovalova S N Kachko A A Protopopova E V Nikolaev L G Loktev V B Sverdlov E D |
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| Institution: | Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, GSP Moscow, 117997 Russia. bgg@humgen.siobc.ras.ru |
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| Abstract: | The genes that were induced and suppressed in human embryonic kidney cell line RH upon the infection with tick-borne encephalitis virus were studied by the method of subtractive hybridization. The expression of interferon-induced genes IFI-54K and IFI-56K in the infected cells was found to increase 50-100-fold. |
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