Phase locking of biological clocks |
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Authors: | F C Hoppensteadt J P Keener |
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Institution: | (1) Department of Mathematics, University of Utah, 84112 Salt Lake City, UT, USA |
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Abstract: | Radial isochron clocks (RICs) and their response to external signals and coupling with other RICs are studied. RICs are derived as phase approximations to self-sustained oscillators. Their response to single impulses (phase resetting) and to repetitive impulses is determined. This response may be harmonic or chaotic. Finally, the effect of coupling between clocks is studied. Simple coupling is shown to exhibit rhythm splitting like that observed in fish and small mammals. New phase locking results for general weakly coupled RIC systems are also derived.Supported in part by the National Science Foundation under grants MCS-80-15359 (FCH) and MCS-79-02505 (JPK) |
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Keywords: | Biological clocks Nonlinear oscillations Phase locking Method of averaging |
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