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Cyclobutane derivatives as potent NK1 selective antagonists |
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| Authors: | Wrobleski Michelle Laci Reichard Gregory A Paliwal Sunil Shah Sapna Tsui Hon-Chung Duffy Ruth A Lachowicz Jean E Morgan Cynthia A Varty Geoffrey B Shih Neng-Yang |
| Institution: | Chemical Research Department, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA. |
| Abstract: | A series of novel cyclobutane derivatives as potent and selective NK1 receptor antagonists is described. Several compounds in this series exhibited high in vitro binding affinity (Ki |
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