Isolation and sequence of a non-opioid peptide derived from proenkephalin |
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| Authors: | R V Lewis P Ray R Blacher A Stern |
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| Institution: | 1. Department of Biochemistry, University of Wyoming, Laramie, WY 82171 USA;2. Department of Molecular Genetics, Hoffmann-La Roche Inc., Nutley, NJ 07110 USA |
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| Abstract: | A non-opioid peptide derived from adrenal proenkephalin has been isolated and sequenced. The sequence of this peptide is Ser-Pro-His-Leu-Glu-Asp-Glu-Thr-Lys-Glu-Leu-Gln (Proenkephalin 168-180). This sequence represents the portion of Peptide I that is cleaved to yield Peptide E. This peptide is processed in a similar manner to the opioid peptides and is present at approximately the same level as Peptide E. |
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| Keywords: | To whom correspondence should be addressed |
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