Thirty years of heme peroxidase structural biology |
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Authors: | Thomas L. Poulos |
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Affiliation: | Departments of Molecular Biology & Biochemistry, Chemistry, and Pharmaceutical Sciences, University of California-Irvine, Irvine, CA 92697-3900, USA |
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Abstract: | The following is a brief review of peroxidase structural biology since the initial structure determination of cytochrome c peroxidase (CCP) 30 years ago. An emphasis will be placed on what CCP has taught us about peroxidase mechanisms, especially Compound I formation and electron transfer. |
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Keywords: | Crystallography Protein engineering Electron transfer Peroxidase |
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