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Effect of super high magnetic field on lysogenic lambda phage with a temperature sensitive repressor
Authors:Kazumasa Okuno  Takashi Ano  Makoto Shoda
Institution:(1) Research Laboratory of Resources Utilization, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, 227 Yokohama, Japan
Abstract:Summary Escherichia coli where bacteriophage lambda was lysogenic was grown under the super high magnetic field (11.7 Tesla) and the effect of the field on the transition from lysogenic to lytic process of the phase was investigated. The occurrence of phage particles due to induction of phage was stimulated under 11.7 T in comparison with that in geomagnetic field by raising temperature from 30 to 45°C. Especially at 35°C, the phase titer was tenfold larger. No significant effect of the field on the phase particleper se was observed. A potential application of high magnetic strength as a controlling factor ofin vivo switching was implied.
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