Improved protection by recombinant BCG |
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| Authors: | Nasser Eddine Ali Kaufmann Stefan H E |
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| Institution: | Department of Immunology, Max-Planck Institute for Infection Biology, Schumannstr. 21/22, 10117 Berlin, Germany. |
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| Abstract: | Mycobacterium bovis bacille Calmette Guérin (BCG) is one of the most widely used live vaccines. Technologic advancement in genome manipulation enables the construction of recombinant BCG (rBCG) strains, which can be employed as highly immunogenic vaccines against tuberculosis with improved safety profile. |
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