The action of excessive,inorganic silicon (Si) on the mineral metabolism of calcium (Ca) and magnesium (Mg) |
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Authors: | Jacek Najda Jan Gmiński Marian Dróżdż Alojzy danch |
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Institution: | (1) Department of Biochemistry and Chemistry, Silesian Medical Academy, ul. Medyków 18, 40-752 Katowice, Poland |
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Abstract: | The influence of silicon treatment on the levels of calcium and magnesium in blood serum and tissues was studied in rats.
The concentrations of both elements were estimated in samples of sera and tissues of rats receiving per os a soluble, inorganic
silicon compound—sodium metasilicate nonahydrate (Na2SiO3·9H2O (REACHIM, USSR)), dissolved in the animals' drinking water. A decrease of magnesium concentration in serum was observed
with accompanying elevation of registered calcemia. Moreover, a reduction of tissue calcium levels was found with a simultaneous
increase of magnesium tissue pool.
The results provide evidence for silicon involvement in mineral metabolism. It could result in a modification of pathological
processes concerning bone tissue. |
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Keywords: | silicon calcium magnesium mineral metabolism |
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