Dihydroxynortropane alkaloids from calystegine-producing plants |
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Authors: | Asano N Yokoyama K Sakurai M Ikeda K Kizu H Kato A Arisawa M Höke D Dräger B Watson A A Nash R J |
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Affiliation: | Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan. naoki22@po.incl.ne.jp |
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Abstract: | Three dihydroxynortropanes, 2alpha,7beta-dihydroxynortropane, 2alpha,3beta-dihydroxynortropane, and 3alpha,7beta-dihydroxynortropane, were isolated from calystegine-producing plants in the families Convolvulaceae and Solanaceae. 2alpha,7beta-Dihydroxynortropane was isolated from six species in the Convolvulaceae whereas only Calystegia soldanella contained it and 2alpha,3beta-dihydroxynortropane. Although neither of these were detectable in three species tested in the Solanaceae, 3alpha,7beta-dihydroxynortropane was, however, isolated from Duboisia leichhardtii. |
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