Histopathology of the dentomaxillary system in experimental fluorosis]

Dynamics of experimental dental fluorosis and regress of the process were studied on albino rats. Fluorine produced a selective toxic action on the tissues of the permanently growing incisors causing disturbances of the dentine- and amelogenesis, and also derangement of the pulp circulation. Changes in the bone tissue of the jaws were characterized by the progressive porosity phenomena. It appeared that regress of the process required a definite duration of the restorative period.