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逆转录病毒与转基因鸡
引用本文:满朝来,陈岩.逆转录病毒与转基因鸡[J].中国生物工程杂志,2007,27(7):117-121.
作者姓名:满朝来  陈岩
作者单位:哈尔滨工业大学生命科学与工程系 哈尔滨工业大学生命科学与工程系
基金项目:国家高技术研究发展计划(863计划)
摘    要:摘要:随着生物制药业的迅速发展,转基因鸡输卵管生物反应器正逐渐成为人们关注的焦点,转基因鸡以其卓越的优势必将成为科学研究的热点和生物制药领域的新兴产业之一。目前,转基因鸡最成功的制备方法即逆转录病毒介导法,并已成功制备出表达标记基因的转基因鸡。本文主要综述了逆转录病毒载体制备转基因鸡的优势,逆转录病毒制备转基因鸡的方法和转基因鸡的研究进展,同时也讨论了转基因鸡的意义和存在问题。

关 键 词:转基因鸡  逆转录病毒  生物制药  
收稿时间:2007-04-11
修稿时间:2007-04-112007-04-23

Retrovirus and Transgenic Chicken
MAN Chao-lai,CHEN Yan.Retrovirus and Transgenic Chicken[J].China Biotechnology,2007,27(7):117-121.
Authors:MAN Chao-lai  CHEN Yan
Institution:Department of Life Science and Engineering , Harbin Institute of Technology, Harbin 150001, China
Abstract:With the fast development of biopharmacy,transgenic chicken oviduct bioreactor is going to be the focus of people's attention.For its excellent advantages,transgenic chicken will be one of rising industries in the field of biopharmacy and hot spot of science study.Now,the most successful method for producing transgenic chicken is mediated by retrovirus transferring gene into it, and transgenic chicken have been produced by this method.The review mainly summarizes the advantages and methods of producing transgenic chicken by retrovirus,and the progress in transgenic chicken research.The significance and existent problems of transgenic chicken are also discussed.
Keywords:Transgenic chicken Retrovirus Biopharmacy
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