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Helicobacter pylori Infection Modulates Host Cell Metabolism through VacA-Dependent Inhibition of mTORC1
Authors:Ik-Jung Kim  Jeongmin Lee  Seung J. Oh  Mee-Sup Yoon  Sung-Soo Jang  Robin L. Holland  Michael L. Reno  Mohammed N. Hamad  Tatsuya Maeda  Hee Jung Chung  Jie Chen  Steven R. Blanke
Affiliation:1. Department of Microbiology, University of Illinois, Urbana, IL 61801, USA;2. Department of Biochemistry, University of Illinois, Urbana, IL 61801, USA;3. Department of Cell and Developmental Biology, University of Illinois, Urbana, IL 61801, USA;4. Department of Molecular and Integrative Physiology, University of Illinois, Urbana, IL 61801, USA;5. Department of Pathobiology, University of Illinois, Urbana, IL 61801, USA;6. Institute for Genomic Biology, University of Illinois, Urbana, IL 61801, USA;7. Department of Molecular Medicine, School of Medicine, Gachon University, Incheon 406-840, Republic of Korea;8. Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan;9. Lead Contact
Abstract:
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  • Keywords:VacA  vacuolating cytotoxin  metabolism  mTORC1  mTOR  autophagy  mitochondria  mitochondrial dysfunction  amino acid homeostasis  Ulk 1
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