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Pax genes and their roles in cell differentiation and development |
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| Authors: | Ahmed Mansouri Marc Hallonet Peter Gruss |
| Affiliation: | Department of Molecular Cell Biology, Max-Planck Institute for Biophysical Chemistry, Am Fassberg 11, D-37077 Göttingen, Germany |
| Abstract: | Members of the Pax gene family are expressed in various tissues during ontogenesis. Evidence for their crucial role in morphogenesis, organogenesis, cell differentiation and oncogenesis is provided by rodent mutants and human diseases. Additionally, recent experimental in vivo and in vitro approaches have led to the identification of molecules that interact with Pax proteins. |
| Keywords: | Abbreviations: BMP bone morphogenetic protein EnEngrailed FGF fibroblast growth factor sey small eye Shh Sonic hedgehog |
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