Antimicrobial activity of the extracts from fruits of <Emphasis Type="Italic">Rumex</Emphasis> L. species |
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Authors: | Magdalena Wegiera Urszula Kosikowska Anna Malm Helena D Smolarz |
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Institution: | 1.Department of Pharmaceutical Botany,Medical University,Lublin,Poland;2.Department of Pharmaceutical Microbiology,Medical University,Lublin,Poland |
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Abstract: | This study was designed primarily to investigate the antibacterial and antifungal activity of the extracts from fruits of
six Rumex L. species: R. acetosa L., R. acetosella L., R. confertus Willd., R. crispus L., R. hydrolapathum Huds. and R. obtusifolius L. The 7 Grampositive and 7 Gram-negative bacteria strains and 5 fungal ones were tested by agar and broth dilution method.
Determination of minimal inhibitory concentration (MIC) revealed that the extracts from R. confertus, R. crispus, R. hydrolapathum and R. obtusifolius exerted differential inhibitory effect on the growth of Gram-positive bacteria — staphylococci (MIC=62.5–125 μg/mL) and Gramnegative
bacteria — Escherichia coli ATCC 3521, Proteus mirabilis, Pseudomonas aeruginosa (MIC=125→500 μg/mL); MIC values determined by agar dilution method were somewhat higher. The same extracts inhibited also
the growth of fungi — Candida spp. or Trichophyton mentagrophytes ATCC 9533 (MIC=250–500 μg/mL), as found by agar dilution method. The total content of polyphenols (11.66–78.36 mg/g), anthracene
derivatives (0.26–12.93 mg/g) and tannins (4.00–11.16%) was also determined. |
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